A No Observable Adverse Effects Level (NOAEL) for pigs fed melamine and cyanuric acid
نویسندگان
چکیده
منابع مشابه
Melamine and Cyanuric acid
Introduction......................................................................................................................... 1 Uses and possible human exposure ................................................................................... 2 Toxicity of Melamine .......................................................................................................... 2 Toxicity of ...
متن کاملEvaluation of the renal effects of experimental feeding of melamine and cyanuric acid to fish and pigs.
OBJECTIVE To determine whether renal crystals can be experimentally induced in animals fed melamine or the related triazine compound cyanuric acid, separately or in combination, and to compare experimentally induced crystals with those from a cat with triazine-related renal failure. ANIMALS 75 fish (21 tilapia, 24 rainbow trout, 15 channel catfish, and 15 Atlantic salmon), 4 pigs, and 1 cat t...
متن کاملTitle: Melamine-Cyanuric Acid Detection System for Purposely Adulterated Foods
Melamine (2,4,6-triamino-1,3,5-triazine) has been used on numerous occasions by individuals as a food adulterant to boost the apparent nitrogen content of food. Together with cyanuric acid, melamine causes acute kidney failure. In the recent infant formula incident, 150,000 children were hospitalized and several died. The WHO recently requested the development of a rapid method to quantitativel...
متن کاملIncreased Nephrotoxicity after Combined Administration of Melamine and Cyanuric Acid in Rats
Renal toxicity by melamine in combination with cyanuric acid (1:1) was investigated. Male rats were orally administered melamine plus cyanuric acid (5, 50 or 400 mg/kg each) for 3 days. In contrast to a negligible effect by melamine alone (50 mg/kg, a no-observed-adverse-effect-level: NOAEL), co-administration with cyanuric acid markedly increased the concentrations of blood urea nitrogen and c...
متن کاملInterference in Melamine–based Determination of Cyanuric Acid Concentration
Isocyanuric acid (commonly referred to in the swimming pool/spa industry as cyanuric acid, stabilizer, conditioner, CYA, etc., and referred to simply as cyanuric acid in this paper) is a member of the symmetrical triazine family, and it is used in outdoor swimming pools and spas to protect chlorine against loss from ultraviolet radiation from the sun. Depending on factors such as season and cli...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Regulatory Toxicology and Pharmacology
سال: 2011
ISSN: 0273-2300
DOI: 10.1016/j.yrtph.2011.05.004